FYI...
I raised this as an incident and support have told me to increase the procedure cache
From the sp_monitorconfig output in the sybdiag, the procedure cache, Reuse_cnt value is 59073.
As per KBA 2122156 (attached to the incident for your review), point 6: "A value other than zero for the Num_Reuse output from sp_monitorconfig also indicates a shortage of procedure cache."
Therefore, you need to consider increasing the size of your procedure cache. Please refer to the
product documentation for instructions and best practices on that matter.